Generation of Human iPSC-Derived Duchenne Muscular Dystrophy Skeletal Myocytes Suitable for 3D Functional Studies and Investigating Methods for Dystrophin Restoration
Figure 1: Calcium flux of wild type (WT) ioSkeletal Myocytes under twitch (left) and tetanic (right) stimulation using Fluo-4AM, 1.2s after initial stimulation.
Our groundbreaking microphysiological system establishes a path towards creating more physiologically relevant biomimetic models for advancing drug development and disease modeling
